SelectSim - Selected Events Linked by Evolutionary Conditions in Cancer
Implements the 'SelectSim' methodology for identifying
patterns of co-occurrence and mutual exclusivity between
functional genomic alterations in cancer cohorts. The package
processes mutation annotation data, constructs alteration
matrices, estimates expected alteration-pair frequencies, and
quantifies deviations associated with selective interactions.
The methodology is described in Iyer et al. (2026)
<doi:10.1038/s41588-026-02661-4>.